The world of skincare is a constantly evolving landscape, overflowing with novel ingredients that promise to turn back the hands of time and achieve a youthful, flawless complexion. One such ingredient making a recent splash and causing a stir in the K-beauty world is PDRN, sometimes referred to as "salmon DNA". It is the main ingredient in KAHI's Wrinkle Bounce Multi Balm, the viral product that gained popularity due to features in media such as Netflix's "Extraordinary Attorney Woo" and Doja Cat's "Vegas" music video.

Let's dive deeper into the science behind PDRN and explore whether the hype surrounding it is truly justified.

What on earth is PDRN?

PDRN stands for Polydeoxyribonucleotide , a fancy term for a complex molecule derived from salmon sperm DNA. Yes, you read that right! While the concept of fish DNA in skincare might raise eyebrows, PDRN has captured the attention of the Korean beauty industry for its potential to promote youthful-looking skin.

Here's what makes PDRN so intriguing: it mimics the natural building blocks found in our own DNA. It works by targeting a specific agent that promotes wound healing when stimulated. Deoxyribonucleic acid (DNA) , for those who remember high school biology, is the blueprint for life, containing the instructions for creating proteins and other essential molecules within our cells. PDRN specifically targets a type of DNA called Polydeoxyribonucleotides , which are believed to play a role in cell repair and regeneration.

This biomimetic approach, where a synthetic material mimics a natural substance, is a growing trend in Korean skincare. Basically, the theory behind PDRN is that by introducing these Polydeoxyribonucleotides derived from salmon sperm to our skin, we can stimulate our own cells to function more optimally, leading to a more youthful appearance.

Now, you may be wondering, why salmon and why salmon sperm? This choice is driven by its high compatibility with human cellular function. Studies have shown that salmon sperm DNA can promote increased skin elasticity and collagen production, both essential for maintaining a youthful appearance. Additionally, salmon sperm is a cost-effective source due to its high DNA content. The extraction and purification process plays a crucial role in ensuring safety. PDRN undergoes rigorous filtering to remove potentially irritating proteins and peptides. This results in a highly purified product rich in DNA, minimizing the risk of adverse skin reactions.

How does PDRN work on the skin?

So, how exactly does salmon DNA translate to smoother skin? PDRN is believed to work by stimulating the production of collagen and elastin, the two superheroes responsible for keeping your skin plump and firm. Here's a breakdown of the potential benefits of PDRN:

• Revitalization : PDRN stimulates microvessels in the skin, promoting tissue regeneration and activating fibroblasts, the cells responsible for collagen production. This results in firmer, plumper skin.
• Enhanced Repair : PDRN penetrates deeper layers of the skin, promoting repair and improving elasticity. It also strengthens the skin's natural barrier, shielding it from future damage.
• Accelerated Renewal: PDRN acts as a catalyst for skin regeneration, promoting a healthy, radiant glow that lasts.
• Collagen and Elastin Boost : This ingredient stimulates the production of both collagen and elastin, the building blocks of youthful skin.
• Even Tone : PDRN helps diminish dark spots and discoloration, leaving you with a brighter and more even complexion.
• Reduced Inflammation : By working at the cellular level, PDRN reduces inflammation, promoting healing and minimizing puffiness.
• Biocompatible Choice : As a naturally occurring substance, PDRN boasts excellent biocompatibility with human skin, minimizing the risk of adverse reactions.

How is PDRN applied to the skin?

PDRN is often used in injectable treatments and high-end skincare products. In Korea, PDRN injections are widely available as an anti-aging treatment at aesthetic clinics. It can also be incorporated into your skincare routine through various methods, all promoting skin regeneration.

Topical Serums: A convenient option, serums are massaged into the skin for maximum absorption. They can be used alone or during facials. One such example is the PDRN Essence 100 from VT Cosmetics, which claims to boost radiance and skin elasticity. It features a low molecular vegan PDRN extracted from wild ginseng, that revitalizes skin and enhances firmness. It is also supported by other beneficial ingredients such as panthenol, squalene and allantoin, with the aim of nourishing and promoting skin healing.

Facial Masks: These non-invasive masks offer a popular way to deliver PDRN. Frequency varies depending on your skin type, ranging from one to three times a week, or even daily for some. Repairing masks often combine PDRN with other beneficial ingredients like adenosineto further enhance tissue regeneration and hydration. For example, the REJURAN Healer Skin Protection Mask is a multi-functional mask pack with brightening, soothing, moisturizing, nourishment and wrinkle care functions. It is formulated with c-PDRN®, adenosine, and aloe vera, all aimed at delivering nutrients and soothing effects to the skin to support its healing process.

Want to formulate your own PDRN product?

This innovative ingredient offers exciting possibilities for promoting youthful radiance and healthy skin. For just $199, you can kickstart your research and development process with a custom formulation and receive a sample that brings your dream product to life.

Start R&D for a custom product today!